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Moreover, inhibition of autophagy combined with irradiation induces a potent antitumor effect in PD-L1-deficient lung cancer mouse models via cGAS-STING-mediated T-cell activation, suggesting a possible combination therapy of irradiation, anti-PD-L1 immune checkpoint blockade and autophagy inhibition in patients with lung cancer (218)

A stainless-steel bone screw was implanted above the cerebellum and served as the grounding and reference electrode

Beside scavenging free radicals and recycling the other antioxidants, glutathione is needed for phase 2 liver detoxification and also plays a very important role in immune function, specifically the specialized immune cells of the brain, called glial cells

Parasites were cultured during the course of the experiment in the appropriate gaseous mix at 37 C in a sealed modular incubator chamber (Billups-Rothenberg, flushed with the same gaseous mix