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The liver also plays a role in the enterohepatic circulationa recycling process where B12 is secreted in bile and reabsorbed in the intestinewhich may be disrupted in advanced disease

Rodrguez Cetina Biefer H, et al

Gilead said the company will work with insurers, health care systems and other payers with the goal of ensuring broad insurance coverage for Yeztugo. Out-of-pocket costs for uninsured patients who take Truvada and Descovy, which Gilead also markets, can range from $22,000 to $30,000 a year, according to an analysis by GoodRx, which provides pharmacy drug pricing information