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These results indicated that berberine may reduce LOX-1 expression through ET-1 receptors both in vitro and in vivo

Anti-hyperglycaemia effects of rutin include reducing the absorption of carbohydrates in the small intestine, inhibiting tissue gluconeogenesis, increasing tissue glucose uptake, stimulating Cells to secrete insulin, and protecting the Langerhans islet from degeneration (27)

In hepatocellular carcinoma, hypoxia upregulates SLC7A11 by inhibiting the expression of methyltransferase 14 (METTL14), further suppressing ferroptosis (211)

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Pliakou X.I., Koutsouka F.P., Damigos D., Bourantas K.L., Briasoulis E.C., Voulgari P.V