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Another study using the chronic mild stress paradigm revealed that mice with decreased sucrose preference and increased immobility in the tail suspension test (i.e., learned helplessness) also showed damaged mitochondrial ultrastructure, impaired respiration rates, and altered membrane potentials in the hippocampus, hypothalamus, and the cortex (Gong et al., 2011)

Although this did not allow for monitoring of diet adherence through traditional dietary research methods, this participant education provided a means to increase self-efficacy in disease symptom management