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[0208] In some embodiments, the mitophagy stimulant is urolithin A (3,8- dihydroxybenzo[c]chromen-6-one)

Although standard therapeutic modalities, including surgery, radiotherapy, chemotherapy, targeted therapy and immunotherapy, have improved, their clinical efficacy is often compromised by drug resistance, tumor microenvironment remodeling and immune evasion (2)

Se estn realizando investigaciones para determinar si puede favorecer la funcin cardaca, especialmente en ciertas afecciones metablicas o cardacas

This incubation immobilizes the protein in a resin slurry, where the resin may contain just one ligand or multiple ligands if higher purification and recovery is desired