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Hence, we next directly investigated whether MRP-1 is involved in the avoidance response to P

3.1 Pharmacokinetic and Pharmacodynamic Considerations After oral and rectal administration of mesalazine, a considerable amount of the drug is excreted unabsorbed with the faeces [17]

These studies all indicate that combined therapeutic strategies integrating multiple active components through hydrogels show significant advantages over single therapies, making hydrogels a promising biomaterial in IDD treatment