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Therefore, the enrichment of these markers, even in non-integrated datasets, suggests a robust compensatory response to mitochondrial stress, a hallmark of ageing previously quantified via metabolic assays in bone marrow ECs 53

Other possible causes of acanthosis nigricans include Addison's disease, pituitary gland disorders, growth hormone therapy, hypothyroidism, or the use of oral contraceptives

Autophagy, reactive oxygen species and the fate of mammalian cells

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