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Studying mice, we found that synapses become stronger while the mice were awake and weaker during sleep by removal of the neurotransmitter receptors called AMPA receptors

Other factors that contribute to AD-related depressive behaviors include a deficiency in melatonin (Nie et al., 2017), impaired glucose metabolism, mitochondrial dysfunction and reduced levels of adenosine triphosphate (ATP) (Li et al., 2024)