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334 Interfering RNA or antisense RNAbased therapy constitutes another method to suppress the Wnt/-catenin pathway, showing suppressive effect to HCC in vitro 335,336 and in mouse models

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Because of these findings, the possibility of inhibiting necroptosis by interfering with and reducing the activity of necrosome components is being considered as new therapeutic targets for treatment (Caccamo et al., 2017)

METTL1-Mediated m7G tRNA Modification Promotes Lenvatinib Resistance in Hepatocellular Carcinoma