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The analogues, 1,8-diMQ and 5-amino-1MQ were tested at concentrations from 200 M-10 nM and 600 M-10 nM, respectively

In addition, exogenous IGF-1 administration has been shown to reduce serum glucose levels [95, 143, 144], not only in healthy individuals [140, 145147], but also in those with insulin resistance [148, 149], type I [150152], and T2D [153155]

The objective is to help investigators choose appropriate controls, align assay selection with the mechanistic question, and report key handling details so results can be interpreted in a way that supports follow on experiments and cross project comparison

Higher NAD+ levels are critical for mitochondrial health, DNA repair, and longevity research