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The study also demonstrated increased collagen and elastin production in human dermal fibroblasts treated in vitro

This is not a speculative concern it is precisely why parenteral nutrition copper dosing is an order of magnitude lower than oral intake, at 0.30.5 mg/day, and why the dose is reduced, with monitoring of serum concentrations, in cholestasis where biliary excretion is impaired

I slipped into bad habits and drank wine and pizzas