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177 Hormones like estrogen and relaxin can alter the synthesis and degradation of collagen, affecting its density, cross-linking, and alignment

doi: 10.1016/j.neuint.2020.104850 63 GhisleniG.KazlauckasV.BothF

Because we previously reported that old C57BL/6J mice and older adults share many age-associated abnormalities [14,22,64], these mice were an ideal to conduct our investigation of cognitive decline and brain abnormalities in aging