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Ellagic acid effect on the components of metabolic syndrome, insulin sensitivity and insulin secretion: a randomized, double-blind, placebo-controlled clinical trial

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However, conditions affecting the gastrointestinal tractincluding pernicious anaemia, Crohn's disease, coeliac disease, or gastric surgerycan significantly impair absorption, necessitating alternative supplementation routes such as intramuscular hydroxocobalamin injections, which deliver B12 directly into the bloodstream

Spermidine and spermine can exert bone protective effects , where they prevent ovariectomy-induced bone loss by inhibiting osteoclast differentiation and maturation without impairing cell viability