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Description

We also solved the crystallographic structures of the C408S, C201S/C408S, and C201S CstB mutants to 2.48 , 2.48 and 3.11 resolution, respectively, by molecular replacement with the wild-type enzyme (see Table S1 for crystallographic statistics)

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Intrathecal administration is a relatively invasive procedure that must be performed by a trained healthcare provider

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Your body adjusting to the medication is a biological reality, not a treatment failure

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& Fehr, A

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