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Each parameter was cross-referenced with experimental data to ensure that the numerical simulations aligned with real-world biological phenomena

Metab Eng 20:131145 Schafer FQ, Buettner GR (2001) Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

Cysteine-specific modification is typically achieved by reaction of the thiol group with electrophiles such as maleimides, iodoacetamides, alkyl halides, and pyridyl disulfides 4,5

Despite challenges related to sample heterogeneity and data standardization, network medicine integration has facilitated the development of comprehensive maps that facilitate molecular interactions, thereby laying the groundwork for developing targeted therapies