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Interestingly, initial data suggest that the Ctr effector TmeA might activate N-WASP like EspF U does which would imply that Cpn has evolved a completely different mechanism for F-actin polymerisation and branching, possibly as an adaptation to the different target tissues involved ( Cpn : lung epithelia

This is the form used in the methylation cycle and may be the most beneficial form for methylation support, especially for those with genetic SNPs, including MTHFR, in the methylation pathway