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Depressive symptoms may appear for the first time after withdrawal, sometimes after a delay of a few weeks, and it can be severe and protracted for some months

Vegetarians, people who've had weight loss surgery, and anyone taking medications for acid reflux or diabetes are also commonly affected

A phase I/II study (NCT02514668) assessed the response to isatuximab monotherapy in daratumumab-refractory patients [77]

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