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Folate (Folate vs Folic Acid) Folate supports DNA synthesis and early fetal neural tube development

NRF2 is a crucial regulatory factor that maintains intracellular redox homeostasis

This review highlights the interconnected metabolic and neuronal mechanisms in Parkinsons disease encompassing -synuclein pathology, sirtuin imbalance, and disrupted insulin signaling role in PD and explores incretin and phytomolecules molecule based therapies, often utilized for type 2 diabetes management as complementary multi-target neuroprotective strategies