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HUVECs grown in the 3D model exhibited not only a markedly elevated level of oxidative stress, expressed by an increased level of malondialdehyde and superoxide dismutase activity inhibition, but also an increased inflammatory response with more secretion of IL-1 and IL-6 in response to TNF- when compared to ECs grown on 2D TCPs

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Bruguera-Avila and colleagues evaluated the effect of nebulized colistin solution (80 mg twice daily for 1 year) on the number of severe exacerbations requiring hospitalizations and on the length of hospitalizations in patients with COPD who were colonized with P