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Once opened, it offers zero antimicrobial protection, and any reconstituted solution becomes vulnerable to contamination

The ability to generate the strong non-radical oxidant HOCl from H 2 O 2 in the presence of chloride ions, however, has been thought to be unique to MPO among the mammalian heme peroxidases, serving as a biochemical fingerprint for the presence of enzymatically active MPO in tissue [157, 158]

Ferreira C, Vieira P, S H, Malva J, Castelo-Branco M, Reis F, Viana S

Therefore, the enhancement of both intra- (inside) and extra-muscular (outside) buffering of H + should lead to an increase in performance where metabolic acidosis is a limiting factor