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The exact cause of this nerve damage is unknown, but many The viruses and bacteria that have been linked to the development of Bells palsy include: herpes simplex, which causes cold sores and genital herpes HIV, which damages the immune system sarcoidosis, which causes organ inflammation herpes zoster virus, which causes chickenpox and shingles Epstein-Barr virus, which causes mononucleosis Lyme disease, which is a bacterial infection caused by infected ticks Many The thought is that the facial nerve reacts to the infection by swelling, which causes pressure in the bony canal (known as the Fallopian canal) that the facial nerve passes through to the side of the face

ENA, extractable nuclear antigen

Queval et al., 2009

The relative cell viability, expressed as a percentage of DMSO- or compound-treated cells under erastin treatment, is summarized as a heatmap (Fig