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10.1016/j.cell.2006.09.024 90

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60 Senescence Senescence is the permanent arrest of the cell cycle, and it is well accepted as one of the major barriers to inhibiting tumorigenesis

Therefore, the resolution phase is much more extended than young mice

For redox metabolism we investigated total (tGSH) and free (fGSH) reduced glutathione, oxidized glutathione (GSSG), the total and free glutathione redox ratios, total cysteine, glutamyl-cysteine and cysteinyl-glycine