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44 Additionally, in patients who are already taking some form of oral B 12 supplementation, demonstrating B 12 deficiency can be a challenge, even when symptoms are typical (including those of neuropathy-like paraesthesia and numbness) as serum B 12 concentrations may be just within, or sometimes above, the normal range

In a separate trial, topical GHK-Cu was compared head-to-head with vitamin C cream and retinoic acid for collagen improvement

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