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Furthermore, F 2 -IsoPs have been shown to increase in different biofluids over the human lifespan (Reference Montine, Peskind and Quinn67) and to be higher in elderly versus younger subjects (Reference Sekhar, Patel and Guthikonda21)

Constitutive activation of G protein-coupled receptors and diseases: insights into mechanisms of activation and therapeutics

Mice were intraperitoneally injected with pregnant horse serum gonadotropin (10 IU, Ningbo Sanseng Pharmaceutical Co., Ltd, Zhejiang, China)