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Studies suggest that phloretin inhibits cancer cell growth in a p53-dependent manner and causes cell cycle arrest

Therefore, both neuroprotective and cardioprotective effects were assumed (Francik et al., On the other hand, cornuside ( 6 ) as a representative for secoiridoid glycosides turned out to be an inhibitor of -site amyloid precursor protein cleaving enzyme 1 (BACE1

The essence of ferroptosis lies in abnormal iron-related metabolism within cells, leading to intracellular redox imbalance, causing lipid peroxide metabolism disorder, and subsequently inducing cell death (Tang et al., 2021