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In this model, pro-inflammatory cytokines/chemokines produced by activated immune cells on the peripheral side of the barrier, or by glial cells in the CNS, contribute to BBB hyperpermeability [4, 42]

Redox Signal 19 , 20242039 (2013)

164 In support of this hypothesis, delivering Cu to the cornea in rabbits could induce the formation of new blood vessels, and Cu has been shown to enhance the proliferation and mobility of endothelial cells