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Interestingly, early studies demonstrated that the Vitamin D receptor (VDR) binds to Vitamin D response elements (VDREs) to induce expression of the human antimicrobial peptide (CAMP) gene, thereby enhancing innate immune function in mammals [238]

Under cadmium stress, these genes are hypothesized to respond by facilitating the scavenging of ROS using GSH to regulate redox homeostasis, promoting the chelation and fixation of GSH with cadmium, or by compartmentalizing cadmium under heavy metal stress

Who it is for: Individuals seeking visible skin brightening, improved skin texture, and anti-ageing support particularly those with chronic sun exposure, post-acne hyperpigmentation, or dull, fatigued-looking skin during summer months

doi:10.1016/s0140-6736(09)61302-7 50Huang S-Z, Liu Z-C, Liao W-X, et al