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78 Son et al

IL-1 enhances MMPs production and the adhesion of leukocytes to RA FLS by activating ERK, c-Jun N-terminal kinase (JNK), apetala (AP)-1, and NF-B (73, 74)

Alcohol oxidation is completed in a two-step reaction by two enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which catalyzes the reduction of NAD + to NADH