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10.18632/aging.202187 Aging 117 LiuS.FuS.WangG.CaoY.LiL.LiX.et al (2021)

doi: 10.1021/acsabm.0c00354 233 JungWAsaduddinMYooDLeeDYSonYKimDet al

Oxidative stress is an imbalance between the production and scavenging of reactive oxygen species (ROS) by the antioxidant defense system, which can cause inflammation

Elevated Ca 2+ levels in the cochlea may link to ROS production as well as triggering apoptotic and necrotic cell death pathways independent of ROS formation (Orrenius et al., 2003)