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524,525 This state of chronic, low-grade inflammation is strongly associated with various diseases and pathologies, including arteriosclerosis, neuroinflammation, osteoarthritis, and intervertebral disc degeneration

burgdorferi sensu lato ( Ixodes ticks which transmit the disease are commonly found throughout temperate regions of North America, Europe, and Asia ( Clinically, Lyme disease presents with dermatologic and/or viral-like signs and symptoms such as intermittent fever, sweats, chills, malaise, fatigue, and achiness during the acute phase, which can transition to neurologic, cardiac, and/or joint involvement in later stages of the infection as the bacteria disseminate hematogenously ( B

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[35] Cardiometabolic disease outcomes [edit] Multiple studies have explored the association between vitamin B 12 and metabolic disease outcomes, such as obesity, insulin resistance and the development of cardiovascular disease