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37 Notably, aging immune cells exhibit impaired secretion of type I interferons (IFN-I), which are downstream effector molecules of cGAS-STING signaling

Trichotillomania can go into remission-like states where the individual may not experience the urge to "pull" for days, weeks, months, or even years

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On the other hand, clinical observations have revealed that elevated peripheral type IFN levels prior to ICI treatment are associated with longer PFS in NSCLC patients [277]