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For example, biejia extract could inhibit PI3K/Akt/mTOR signaling in MDA-MB-231 breast cancer cells, attenuating EMT and metastatic behaviors (Yang et al., 2022)

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The TFIIH subunits of XPD and XPB act as a 5'-3' and 3'-5' helicase, respectively they help unwind DNA and generate a junction between the double-stranded and single-stranded DNA around the transcription bubble

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