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Defining feasibility and pilot studies in preparation for randomised controlled trials: development of a conceptual framework

Blood 134:421431 Dimopoulos M, Quach H, Mateos MV, Landgren O, Leleu X, Siegel D et al (2020) Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): results from a randomised, multicentre, open-label, phase 3 study

However, published phase 3 papers focused primarily on total weight and glycemic control without reporting detailed body composition data comparing lean mass preservation between treatment groups

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