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Randomized controlled trials have demonstrated 60 to 100% reductions in NTD cases when women consumed folic acid supplements in addition to a varied diet during the month before and the month after conception

That does not mean it is unsafe, it means the level of certainty is not the same

More severe side effects include: Advertisement It can be difficult to diagnose vitamin B12 deficiency because you may not have symptoms, or symptoms can be like other nutritional deficiencies

B-Complex as Part of IV Hydration At Minnesota IV Hydration, B-complex vitamins are commonly included in energy-supportive infusions and may be added to other formulations when appropriate