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For an ACO that reports all of the required measures in the APP Plus quality measure set, meeting the data completeness requirement at 414.1340 of this subchapter for all of the required measures in the APP Plus quality measure set, and administers the CAHPS for MIPS survey (except as specified in 414.1380(b)(1)(vii)(B) of this subchapter), CMS calculates the ACO's health equity adjusted quality performance score as the sum of the ACO's MIPS Quality performance category score for all measures in the APP Plus quality measure set and the ACO's health equity adjustment bonus points calculated in accordance with paragraph (b)(4) of this section

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In addition, the deacetylase sirtuin 3 (Sirt3) increases the content of the pyruvate dehydrogenase complex (PDH) through deacetylation, thereby participating in ATP production

J., & Cheong, K