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For example, berberine was found to inhibit cardiac fibroblast proliferation and myofibroblast differentiation by modulating AMPK/PGC-1 signaling, helping to alleviate cardiac fibrosis in models of ischemic or diabetic cardiomyopathy (Hu et al., 2025)

Am J Respir Crit Care Med 166(4):510513 Lok SS, Stewart JP, Kelly BG, Hasleton PS, Egan JJ (2001) Epstein-Barr virus and wild p53 in idiopathic pulmonary fibrosis