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Preclinical research indicates GHK-Cu has the capacity to modulate the expression of over 4,000 human genes, according to bioinformatics analyses conducted by Pickart and colleagues, with a substantial subset of these genes tied directly to extracellular matrix maintenance, collagen production, and tissue-repair signaling

It was originally derived from a protective gastric peptide sequence, and much of the research has focused on mucosal protection, ulcer healing, intestinal inflammation, and gut barrier support

Because it attaches to p53, it can prevent senescent cell death

In addition, it reduces photo-damage and discoloration of the skin, improving its overall appearance