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Furthermore, the accumulation of Nestin + BMSCs in the bone marrow of AML was critical for the viability and proliferation of LSCs in vitro and in vivo , Nestin + BMSCs induced chemoresistance by increasing energy production and glutathione-peroxidase (GPX) activity in LSCs (183)

[DOI] [PubMed] [Google Scholar] 40.Hadi V, Kheirouri S, Alizadeh M, Khabbazi A, Hosseini H

For example, combining ferroptosis inducers with radiotherapy can enhance DNA damage induced by radiotherapy, while combining them with immune checkpoint inhibitors can improve the immune microenvironment

Principles and clinical implications of the brain-gut-enteric microbiota axis