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FDA-approved drugs: These are made by licensed pharmacies (503A or 503B) for specific patients with a valid prescription

Mathematical model reveals role of nucleotide signaling in airway surface liquid homeostasis and its dysregulation in cystic fibrosis

Production of peroxynitrite Nitric oxide alone is not toxic to normal motor neurons (Estvez et al., 1999), but when superoxide is also produced it can react with nitric oxide to form the powerful oxidant peroxynitrite, responsible for the induction of cell death