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DNp73, a dominant-negative variant of the tumor suppressor p73, enhances EMT and cancer stemness by abrogating the inhibitory effect of EPLIN on IGF-IR and downregulating miR-885-5p thereby increasing its direct target IGF-IR [74, 75]

Investigation of the material basis and mechanism of Lizhong decoction in ameliorating ulcerative colitis based on spectrum-effect relationship and network pharmacology