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12 Another crossover trial of eight women found reduced plasma concentrations of pro-inflammatory cytokines and overall symptoms when treated with 8 weeks of LDN, further supporting the hypothesis of LDN as an anti-inflammatory medication for fibromyalgia

Folate (B9) Target: Aim for upper third of local reference range Why it matters: B12 therapy increases demand on folate pathways and can expose low stores

Peer-reviewed and received in revised form 11 January 2022

Pearce et al., 2013), deep hypersaline anoxic basins (Hallsworth et al., 2007), subglacial lakes (Pearce, 2017) or hydrothermal vent systems, such as Lost City (Weber et al., 2023)