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Its primary job is to block an enzyme called nicotinamide N-methyltransferase, or NNMT

The SERCA inhibitor thapsigargin was found to potently induce DRAK2 autophosphorylation on Ser12, supporting the hypothesis that ER store-operated calcium entry modulates DRAK2 catalytic activity

They have been shown to stimulate secretion of peptide hormones from the enteroendocrine cells such PYY and GLP-1, amino acid tryptophan with the associated neurotransmitter serotonin (5-HT: serotonin, 5-hydroxytryptamine), dopamine and GABA (Yano et al., 2015

Our team at Real Peptides deals with the science of these compounds every single day, so let's break down what we know, what the research suggests, and where the real potential lies