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Description

Clin Pharmacol 14 (2022): 6167

The entry of -KG into the TCA cycle is highly regulated: Pyruvate Dehydrogenase Complex (PDC): The conversion of pyruvate to acetyl-CoA is tightly regulated by the PDC complex, which can be inhibited by acetyl-CoA (feedback inhibition) and activated by ADP

7c), which suggested that most of CD44 hi CD8 + memory T cells in the brain are resident, and are unable to circulate due to the lack CD62L to provide sufficient immunity to local infections 45

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