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You should avoid or use the medication with caution if you have: Active malignancy (cancer) Proliferative retinopathy (serious eye disease) Pregnancy, or if you are breastfeeding Severe obesity with sleep apnea (higher risk of complications) Allergy to any ingredient in the medication Untreated hypothyroidism can cause a sluggish thyroid, which can reduce the effectiveness of Sermorelin, leading to limited or poor results

The frequency and dosage of the injections matter a lot, too its all about finding the right balance

This has been demonstrated in multiple studies with rats and swine, where growth hormone levels significantly increased after injections without impacting ACTH and cortisol plasma levels: In pentobarbital anaesthetised rats, ipamorelin released GH with a potency and efficacy comparable to GHRP-6 (ED50 = 80+/-42nmol/kg and Emax = 1545+/-250ng GH/ml vs 115+/-36nmol/kg and 1167+/-120ng GH/ml)

Originally developed to reduce excess abdominal fat in individuals with HIV, Tesamorelin has gained popularity for its ability to stimulate the release of growth hormone, which in turn helps reduce visceral fat and improve body composition