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Moreover, in vivo assessments in a rat model of collagen-induced arthritis revealed effective accumulation of the liposomal drug depot at the inflamed joint site, resulting in macrophage repolarization and cartilage tissue repair

This improvement occurred because nitrogen atoms introduced additional charge carriers through n-type doping, reduced structural defects, and modified the electronic band structure, ultimately leading to lower electrical resistance and enhanced electronic performance

No difference in melting temperature between the non-functionalised and directly functionalised oligonucleotide was observed

The release of TNF induces oxidative stress, which triggers SOD2 expression to promote cellular survival and migration within the altered environment (Psaila And Lyden 2009)