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doi: 10.1093/cvr/cvp305 231 GopalKKarwiQGTabatabaei DakhiliSAWaggCSZhangLSunQet al

GTP cyclohydrolysase 1 (GCH1), the rate-limiting enzyme for BH4 synthesis, also functions as a free-radical trapping antioxidant to inhibit ferroptosis (Zhang et al., 2022)

Pernicious anaemia, an autoimmune loss of intrinsic factor, is the classic one

This suggests that preventive oral iron supplementation may be a suitable measure for reasonable pre-pregnancy iron supplementation in clinical practice (12) and can improve the iron status in a physiological gestational anemia model

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