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J Biol Chem 282(34):2508825099

4.3.2 Effects on oocyte quality during in vitro maturation and growth Recent research has highlighted the significant role of melatonin in improving oocyte quality, particularly in the context of in vitro maturation and growth (87, 88)

Cellular senescence is a stable state of cell cycle arrest accompanied by distinctive phenotypic alterations, among which the acquisition of the senescence-associated secretory phenotype (SASP) is of greatest pathological significance (130, 131)