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In vivo rodent models have explored the interplay between GHRP-6 administration and hypothalamic neuropeptide circuits, particularly regarding orexigenic signalling pathways

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Secondly, d-lactate neurotoxic effect indicates that suppression of neuronal activity during hypoxia alone is not effective in protecting human neurons from ischemic damage, which is consistent with the above-mentioned failure of neuroprotective strategies directed to suppression of neuronal activity during hypoxia 12,13