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have reported that decreased levels of PDGF-B promote vascular normalization of breast cancer cells, increase cytotoxic drug delivery, and inhibit tumor growth 17

AOD-9604 has no cardiovascular data

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For example, the availability of nutrients in the TME affects the metabolic status of cancer and stromal cells, while many metabolites, such as lactate, secreted by cancer cells further promote the formation of an immunosuppressive microenvironment