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Therefore, GSK-3 inhibits autophagy either directly or indirectly via attenuation of Rac1

Bentham Science - BPC 157 and Standard Angiogenic Growth Factors: Lists authors including Sven Seiwerth

reported that astrocyte ablation in chronic experimental autoimmune encephalomyelitis ameliorates pathology, whereas acute-phase ablation worsens disease, illustrating a time-dependent dual role 37

These water molecules are absent from the structure of the Meisenheimer complex bound to GST, implicating that deprotonation of the cysteine occurs during formation of the ternary complex which involves expulsion of the inner bound water molecule